Facts About link thr777 Revealed

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ClinVar has an entry for this variant (Variation ID: 574387). Variants that disrupt the consensus splice web page are a relatively prevalent cause of aberrant splicing (PMID: 17576681, 9536098). Algorithms created to predict the result of sequence changes on RNA splicing suggest that this variant may possibly develop or strengthen a splice website. In summary, the out there evidence is currently inadequate to ascertain the function of the variant in disorder. Hence, it's been labeled for a Variant of Unsure Significance. (significantly less)

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The worldwide minor allele frequency calculated with the 1000 Genomes Job. The minor allele at this area is indicated in parentheses and should be distinctive from your allele represented by this VCV report.

This column consists of additional information supporting the classification, together with citations, the comment on classification, and detailed proof offered as observations of your variant through the submitter.

This column contains additional information supporting the classification, such as citations, the comment on classification, and specific evidence delivered as observations in the variant via the submitter.

The problem for that classification, supplied by the submitter for this submitted (SCV) file. This column also includes the influenced position and allele origin of people noticed using this variant.

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